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Capping Solutions

Capping Solutions

Atom Scientific supply Capping Solutions from EMP Biotech, formulated to efficiently block uncoupled nucleotides during oligonucleotide synthesis. These reagents improve sequence integrity and yield by preventing chain extension at incomplete sites.

 

Our Range Includes...

Capping A Solutions: Acetic anhydride blends in ACN or THF for rapid acetylation.

Ultramild Capping: Phenoxyacetic anhydride-based for sensitive oligos.

Capping B Solutions: Lutidine and N-methylimidazole in ACN or THF for complete reactivity.

AKTA OligoPilot Compatible: Preconfigured for automated synthesis platforms.

 

 

C
Capping A - Acetic Anyhdride in Acetonitrile (Acetonitrile / Acetic Anhydride; V / V = 75 / 25)
Capping A (20% N-methylimidazole in acetonitrile, for AKTA OligoPilot)
Capping A (THF / acetic anhydride; V / V = 90 / 10)
Capping A (THF / lutidine / acetic anhydride; V / V / V = 80 / 10 / 10)
Capping A Ultramild (THF / pyridine / phenoxyacetic anhydride; V / V / V = 85 / 10 / 5)
Capping A, 20% Acetic Anhydride in Acetonitrile (Acetonitrile / Acetic Anhydride = 80 / 20)
Capping B (16% N-methylimidazole in THF)
Capping B (Acetonitril / 2,6-Lutidine / N-methylimidazole; V / V / V = 50 / 30 / 20)
Capping B (THF / pyridine / N-methylimidazole; V / V / V = 80 / 10 / 10)
Capping B1 (40% acetic anhydride in acetonitrile, for AKTA OligoPilot)
Capping B2 (60% lutidine in acetonitrile, for AKTA OligoPilot)
Atom Scientific Ltd