Isonicotinic Acid Hydrazide >98% (HPLC)

What is Isonicotinic Acid Hydrazide?

Isonicotinic Acid Hydrazide (INH), with the molecular formula C6H8N2O, is a white crystalline powder with a slightly bitter taste. It is an important organic compound in the field of pharmaceutical chemistry and is primarily known for its role as a key intermediate in the synthesis of various therapeutic agents. Isonicotinic Acid Hydrazide is most commonly used as the active pharmaceutical ingredient in the treatment of tuberculosis. It exhibits potent bactericidal activity against Mycobacterium tuberculosis, the bacterium responsible for tuberculosis (TB). As a hydrazide derivative of isonicotinic acid, it participates in the inhibition of bacterial cell wall synthesis, ultimately helping to eradicate the infection.

Isonicotinic Acid Hydrazide is primarily used in the pharmaceutical industry, especially in the formulation of drugs used for tuberculosis treatment. It is an essential compound in the development of first-line anti-TB medications, often used in combination with other drugs to ensure effective treatment.

Uses of Isonicotinic Acid Hydrazide:

• Antitubercular Drug: Isonicotinic Acid Hydrazide is the active ingredient in isoniazid (INH), a widely used medication for the treatment of tuberculosis. It helps inhibit the growth of Mycobacterium tuberculosis by interfering with cell wall synthesis.
• Pharmaceutical Synthesis: It serves as a key intermediate in the synthesis of other pharmaceutical compounds, especially in the production of anti-infective agents.
• Research and Development: Isonicotinic Acid Hydrazide is used in laboratory research to explore its antimicrobial properties and in the development of novel treatments for infectious diseases.
• Chemotherapy for Tuberculosis: It is used in combination therapy with other antitubercular agents to treat both active and latent tuberculosis infections, playing a vital role in global TB management.

High-Quality Formulation
Our Isonicotinic Acid Hydrazide is carefully sourced, ensuring consistent performance in pharmaceutical formulations and research applications; meeting the criteria for HPLC grade (high-performance liquid chromatography). It is an essential chemical reagent for TB drug development and manufacturing.

No Additives
We provide Isonicotinic Acid Hydrazide with no added chemicals or preservatives, ensuring that it meets the rigorous standards required for pharmaceutical and research applications.

Shipped from Manchester, UK Facility: Our Isonicotinic Acid Hydrazide is sourced and packaged using non-toxic, chemical-resistant containers, ensuring reliable quality for our customers.

Frequent Uses:

Antitubercular Drug Synthesis
Isonicotinic Acid Hydrazide is an essential precursor in the synthesis of isoniazid (INH), a major drug used in the treatment of tuberculosis. Its primary use in the pharmaceutical industry is in the production of TB medications.

Research and Pharmaceutical Development
It is used in the research and development of new drugs targeting mycobacterial infections, helping to create more effective treatments for tuberculosis and related diseases.

Chemical Reactions in Organic Synthesis
In organic chemistry, Isonicotinic Acid Hydrazide is used as a reagent in various chemical reactions, including the synthesis of hydrazones and other bioactive compounds.

Combination Therapy for Tuberculosis
In tuberculosis treatment regimens, Isonicotinic Acid Hydrazide is often administered in combination with other drugs to treat both active and latent forms of the disease, significantly reducing the risk of drug resistance

Frequent Uses:

Antitubercular Drug Synthesis
Isonicotinic Acid Hydrazide is an essential precursor in the synthesis of isoniazid (INH), a major drug used in the treatment of tuberculosis. Its primary use in the pharmaceutical industry is in the production of TB medications.

Research and Pharmaceutical Development
It is used in the research and development of new drugs targeting mycobacterial infections, helping to create more effective treatments for tuberculosis and related diseases.

Chemical Reactions in Organic Synthesis
In organic chemistry, Isonicotinic Acid Hydrazide is used as a reagent in various chemical reactions, including the synthesis of hydrazones and other bioactive compounds.

Combination Therapy for Tuberculosis
In tuberculosis treatment regimens, Isonicotinic Acid Hydrazide is often administered in combination with other drugs to treat both active and latent forms of the disease, significantly reducing the risk of drug resistance

Assay (HPLC):>98%
Assay (NA Titration): >98%
M.P.: 172 deg C
Solubility (Water): almost transparency

Synonyms: Isoniazid

Cas Number: 54-85-3

Einecs Number: 200-214-6

HS Code / Commodity Code: 2933399990

Hazard Phrases: H302.H315,H319,H371,H373

Prec Phrases: P50,P260,P264,P280,P337+P313,P308+P311