10% Dichloroacetic acid in toluene

Deblocking solutions, used for the cleavage of the 5‘-DMTr group at the last building block of nucleotide chain, can consist either of dichloroacetic or trichloroacetic acid in dichloromethane or toluene.

Our Hyacinth Deblocking solution (3% dichloroacetic acid in toluene at <30 ppm water) is applicable for the syntheses of high quality, large scale oligonucleotides.

Product Name: Deblocking Reagent
Description: Anhydrous mixture containing, 10% Dichloroacetic acid in Toluene, (v/v)
CAS Number: Toluene/108-88-3, Dichloroacetic acid/79-43-6
Appearance: Clear Solution
Function Test: positive
Refractive Index: 1,492 – 1,494
Water Content: ≤ 60.0 ppm
Shipping: Ambient
Storage: Ambient

Application Note
High Performance detritylization reagent for nucleic acid synthesis

Cas Number: 108-88-3

Einecs Number: 203-625-9

HS Code / Commodity Code: 38249992

UN Number: 2924

Hazard Class: 3

Packing Group: 2

Hazard Phrases: H225,H304,H315,H318,H336,H351,H360FD,H373,H410

Prec Phrases: P210,P273,P280,P301+P310,P305,P351,P338,P331