Phenylacetyl disulfide (PADS), solid

£52.48 to £1876.07

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Variation ID		Product Code	Pack Size	List Price
15639	photo_camera	NC-0304-E005.0-001	5g NC-0304-E005.0-001	£52.48
15640	photo_camera	NC-0304-E025.0-001	25g NC-0304-E025.0-001	£200.25
15641	photo_camera	NC-0304-E500.0-001	500g NC-0304-E500.0-001	£1876.07

The phosphite triester formed in the coupling step can be converted to the corresponding phosphorothioate triester by treatment with 0.2 M solution of phenylacetyl disulfide (PADS) in acetonitrile and 3-picoline (V / V = 1:1).

Typically, a 1.5-column volume of PADS solution is used, and sulphurization is complete within 3 minutes, at which time excess reagent is recovered from the reaction vessel by washing with acetonitrile.

An alternative sulfur-transfer reagent is 3-amino-1,2,4-dithiazole-5-thione (ADTT, also known as Xanthane Hydride) which is suitable for solid-phase synthesis.

Trade Name(s): PADS
Catalog Number: NC-0304
CAS Number: 15088-78-5
Molecular Formula: C16H14O2S2
Molecular Weight: 302.4 g/ mol
Appearance: White to off-white powder
Identification by IR: The IR spectrum of the test sample should match
with the IR spectrum of working standard
Purity by HPLC: ≥ 98.5 %
Water Content by Karl Fisher: ≤ 300 ppm
Shipping: Ambient.
Storage: < 25 °C.