Variation ID | Product Code | Pack Size | List Price | Qty | |
---|---|---|---|---|---|
PTS6010-1L | 1L | £16.74 | |||
PTS6010-2.5L | 2.5L | £33.48 |
Dichloromethane (also known as methylene chloride) is a widely used solvent in peptide synthesis, a process used to create peptides by chemically joining amino acids together in a specific order. It is a colourless liquid with a sweet, ether-like odour and the chemical formula CH2Cl2. Dichloromethane is a highly volatile and relatively low-boiling solvent, with a boiling point of approximately 40 °C at atmospheric pressure.
Dichloromethane is commonly used as a solvent in peptide synthesis because it is a good solvent for dissolving many reagents, including amino acids and coupling reagents. It is also an excellent solvent for the deprotection of amino acid side chains, which is a crucial step in peptide synthesis. The high volatility of dichloromethane ensures that it evaporates quickly, leaving behind the synthesized peptide.
Dichloromethane is highly purified and free of impurities that may interfere with peptide synthesis reactions. It is available in different grades, including synthesis grade and peptide synthesis grade, each with different levels of purity and suitability for different applications.
Overall, Dichloromethane is a widely used solvent in peptide synthesis due to its ability to dissolve reagents and deprotect amino acid side chains effectively. Its high purity and low boiling point also make it a popular solvent in other organic chemistry applications.