20% Diethylamine in acetonitrile (water content <=20 ppm)

£78.07 to £141.00

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Variation ID		Product Code	Pack Size	List Price	Qty
15590	photo_camera	NC-0302-N001.0-001	1L NC-0302-N001.0-001	£78.07
15591	photo_camera	NC-0302-N002.5-001	2.5L NC-0302-N002.5-001	£141.00

Alkylation of the N3-position of thymidine by acrylonitrile, which is liberated during ß-elimination of the cyanoethyl group from the phosphates, is a well-known side reaction during simultaneous cleavage of the protecting groups and the oligonucleotide from the support.

This side reaction can be avoided by use of diethylamine in acetonitrile for the ß-elimination. The oligonucleotide is subsequently cleaved from the support using any standard cleavage conditions.

Product Name: 20% Diethylamine in Acetonitrile
Description: 20% Diethylamine in anhydrous, Acetonitrile, (v/v)
CAS Number: Diethylamine/109-89-7, Acetonitrile/75-05-8
Appearance: Clear Solution
Refractive Index: 1,351 – 1,353
Water Content: ≤ 50 ppm
Density (g/L): 765.75

Shipping: Ambient
Storage: Ambient