Paraformaldehyde 4% in 0.1M Phosphate Buffer pH 7.4

£16.37 to £52.37

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Variation ID		Product Code	Pack Size	List Price
14297	photo_camera	VM3322-D	500ml VM3322-D	£16.37
14298	photo_camera	VM3322-E	1L VM3322-E	£26.19
14299	photo_camera	VM3322-F	2.5L VM3322-F	£52.37

What is Paraformaldehyde 4% in 0.1M Phosphate Buffer pH7.4? Paraformaldehyde 4% in 0.1M Phosphate Buffer pH7.4 is a solution commonly used in biological and laboratory applications for tissue fixation and preservation. A polymer of formaldehyde, it is dissolved in a phosphate buffer to create a stable solution that helps preserve cellular structures and proteins by crosslinking them, which prevents degradation. The phosphate buffer maintains the pH of the solution, ensuring that the fixation process occurs at an optimal pH level to preserve the integrity of the biological samples. This formulation is widely used in microscopy, histology, and cell biology for preparing tissues for further analysis.

Predominantly used in the preparation of tissue samples for microscopic examination, including immunohistochemistry, electron microscopy, and other histological techniques. It is a standard fixative in research and clinical laboratories for preserving tissue samples without altering their morphology or compromising the quality of subsequent analyses.

High-Quality Formulation: We use only carefully sourced Paraformaldehyde 4% in 0.1M Phosphate Buffer to ensure high-quality fixation and consistency across a range of biological research applications. It is specifically formulated to preserve the integrity of biological samples for various microscopic and histological studies.

Shipped from Manchester, UK Facility: Sourced and bottled using non-toxic, chemical-resistant containers, ensuring reliable quality for our customers.

Dispensing Adapter Compatibility

500ml: 45mm neck size
1L: 45mm neck size
2.5L: 45mm neck size

Frequent uses

Tissue Fixation

The solution is widely used to fix biological tissue samples, preserving cellular structures, proteins, and nucleic acids for further examination under a microscope.

Immunohistochemistry

Commonly used for tissue fixation prior to immunohistochemical staining, which allows researchers to visualize specific proteins and other molecules in tissues.

Electron Microscopy

This solution is often used in electron microscopy for the fixation of cells and tissues, ensuring the preservation of ultrastructural details at the microscopic level.

Histological Studies

In histology, it is employed for the preparation of tissue samples for routine histopathological examination, preserving the tissue architecture for study.

Cell Biology Research

Used in cell biology to preserve the structure of cultured cells for various analyses, including fluorescence microscopy and flow cytometry.

Paraformaldehyde 4% in 0.1M Phosphate Buffer pH 7.4 is commonly used as a fixative in biological research to preserve cells or tissues for further analysis. It can also be used for:

Synthesis of various organic compounds
As a disinfectant in medical and laboratory settings
Preservation of insects, such as butterflies, for display purposes
As a crosslinking agent for proteins in biochemistry
For DNA and RNA extraction from cells and tissues
To prepare samples for transmission electron microscopy
For the preparation of formaldehyde-fixed antigen for use in immunohistochemistry and immunofluorescence staining.